HSF-1 ACTIVATES THE UBIQUITIN PROTEASOME SYSTEM TO PROMOTE NON-APOPTOTIC DEVELOPMENTAL CELL DEATH IN C. ELEGANS

HSF-1 activates the ubiquitin proteasome system to promote non-apoptotic developmental cell death in C. elegans

Apoptosis is a prominent metazoan cell death form.Yet, mutations in apoptosis regulators cause only minor defects in vertebrate development, suggesting that another developmental cell death mechanism exists.While some non-apoptotic programs have been molecularly characterized, none appear to control developmental cell culling.Linker-cell-type death

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Beyond Gap Junction Channel Function: the Expression of Cx43 Contributes to Aldosterone-Induced Mesangial Cell Proliferation via the ERK1/2 and PKC Pathways

Aims: This study aimed to explore the precise mechanism and signaling pathways of mesangial cell (MC) proliferation from a new point of view considering Connexin 43 (Cx43).Methods: Jersey MC proliferation was measured by the incorporation of 3H-thymidine (3H-TdR).Cx43 was over-expressed in MC cells using lipofectamine 2000, and the expression level

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A Hybrid BCI Based on SSVEP and EOG for Robotic Arm Control

Brain-computer interface (BCI) for robotic arm control has been studied to improve the life quality of people with severe Bedding Set motor disabilities.There are still challenges for robotic arm control in accomplishing a complex task with a series of actions.An efficient switch and a timely cancel command are helpful in the application of robotic

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Devolution, the Independence Referendum and Votes at 16 in Scotland: Holyrood, a Pioneer in Democracy Leading the Way for Westminster?

The Scottish Parliament enfranchised 16 Seat Pad and 17-year-olds prior to the 2014 referendum on independence of Scotland from the UK.Scotland was among the very first nations in the world to lower the minimum voting age below 18.The Scottish National Party (SNP) majority Government emphasised the importance of recognising other rights and respons

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