HSF-1 activates the ubiquitin proteasome system to promote non-apoptotic developmental cell death in C. elegans
Apoptosis is a prominent metazoan cell death form.Yet, mutations in apoptosis regulators cause only minor defects in vertebrate development, suggesting that another developmental cell death mechanism exists.While some non-apoptotic programs have been molecularly characterized, none appear to control developmental cell culling.Linker-cell-type death